Effects of recombinant human keratinocyte growth factor on surfactant , plasma and liver 1 phospholipid homeostasis in hyperoxic neonatal rats
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چکیده
Effects of recombinant human keratinocyte growth factor on surfactant, plasma and liver 1 phospholipid homeostasis in hyperoxic neonatal rats 2 Marco Raith; Katharina Schaal; Roland Koslowski, PhD; Heinz Fehrenbach, PhD; 3 Christian F. Poets, MD; Erwin Schleicher, PhD; Wolfgang Bernhard, MD, PhD 4 Departments of Neonatology and of Internal Medicine, Faculty of Medicine, Eberhard-Karls5 University, Tübingen, Germany. Institute of Physiological Chemistry, Faculty of Medicine, 6 University of Technology, Dresden, Germany. 4 Section of Experimental Pneumology, Research 7 Center Borstel, Leibniz Center for Medicine and Biosciences, Borstel, Germany. 8
منابع مشابه
Effects of recombinant human keratinocyte growth factor on surfactant, plasma, and liver phospholipid homeostasis in hyperoxic neonatal rats.
Respiratory distress and bronchopulmonary dysplasia (BPD) are major problems in preterm infants that are often addressed by glucocorticoid treatment and increased oxygen supply, causing catabolic and injurious side effects. Recombinant human keratinocyte growth factor (rhKGF) is noncatabolic and antiapoptotic and increases surfactant pools in immature lungs. Despite its usefulness in injured ne...
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